Male cats can easily develop obstruction of the urethra which is the tube draining urine from the bladder out of the penis. Obstructions are often the result of plugs of inflammatory material, mucus, crystals, small stones (called calculi) that have formed in the kidneys and have passed down into the bladder (see urinary stones). The cause of the inflammatory materials and stone formation it not well understood, though viral infections and diet may play a role. Other causes are reported such as cancer, previous injury causing scarring, and trauma are also reported. Early neutering of cats does not cause reduction of urethral size as in some other species.
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Source:   • urine blockage in male cats