In this episode, I explain the biology of hair, hair growth, why hair growth slows and what causes hair to stop growing and/or “fall out.” I discuss the essential role of hair stem cells and other supporting biological factors for healthy hair growth. Then I describe various approaches (mechanical and chemical) to slow hair loss by increasing blood flow to hair stem cells, including minoxidil, tadalafil, PRP, microneedling, Botox and ketoconazole treatments. I also discuss how agerelated hormone changes cause hair loss and explain the effectiveness of treatments such as caffeine, saw palmetto, growth hormone, finasteride and dutasteride. For all hair growth options, I describe potential side effects, how soon to expect results and the amount of hair regrowth to expect and I highlight effective combination treatments for hair regrowth even in hair “dead” (bald) zones. For many listeners, thinning, brittle hair, or pattern baldness are a source of anxiety and stress. This episode explains the mechanisms underlying hair regrowth tools and the science behind them so that you can evaluate potential treatments and associated sideeffect profiles and select the best one(s) for you.

#HubermanLab #Science #HairGrowth

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HVMN: https://hvmn.com/huberman
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Articles
Microneedling and Its Use in Hair Loss Disorders: A Systematic Review: https://link.springer.com/article/10....
Caffeine and Its Pharmacological Benefits in the Management of Androgenetic Alopecia: A Review: https://www.karger.com/Article/Fullte...
The effectiveness of combination therapies for androgenetic alopecia: A systematic review and metaanalysis: https://onlinelibrary.wiley.com/doi/1...
Differential effects of caffeine on hair shaft elongation, matrix and outer root sheath keratinocyte proliferation, and transforming growth factor‐β2/insulin‐like growth factor‐1‐mediated regulation of the hair cycle in male and female human hair follicles in vitro: https://academic.oup.com/bjd/article...
The structure of people’s hair: https://peerj.com/articles/619/

Note: The Huberman Lab podcast has no affiliation with or financial benefit from any of the products listed below, which are provided as a useful reference only.

Ketoconazole Shampoos
Keeps: https://www.keeps.com/ourproducts/ke...
Nurx: https://www.nurx.com/topical/ketocona...
Siena Health: https://www.sienahealth.com/product/k...
Intelligent: https://intelligent.shop/products/int...

Biotin Shampoos
Maple Holisitics: https://www.amazon.com/BiotinHairSh...
Ouai: https://theouai.com/collections/shamp...
R+Co: https://www.randco.com/collections/da...

Microneedling https://www.amazon.com/s?k=microneedl...

Timestamps
00:00:00 Hair
00:04:13 Sponsors: Helix Sleep, HVMN, ROKA
00:08:04 Psychological States & Hair
00:13:19 Hair Anatomy & Stem Cells
00:26:05 3 Phases of Hair Growth
00:35:40 Sponsor: AG1 (Athletic Greens)
00:36:55 Minoxidil & Blood Flow
00:45:37 Increase Blood Flow: Massage, Tadalafil, PlateletRich Plasma (PRP), Microneedling
00:56:10 Microneedling, Minoxidil & “Dead Zones”
01:00:13 Sponsor: LMNT
01:01:25 Botox Treatments
01:06:27 Androgens, Hair Growth & Pattern Hair Loss; Scalp vs. Beard Hair
01:15:46 Topical Caffeine & Slowing Hair Loss
01:21:06 IGF1: Growth Hormone & Sermorelin; Insulin Sensitivity: MyoInositol
01:25:52 Iron & Hair Growth
01:27:04 5Alpha Reductase & Saw Palmetto; Curcumin
01:33:22 Ketoconazole & Offsetting Hair Loss
01:38:46 Topical & Oral Finasteride
01:51:00 Post Finasteride Syndrome
01:56:01 Dutasteride
01:58:53 Mechanical & Chemical Stimulation for Hair Growth
02:02:46 ZeroCost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Social Media, Neural Network Newsletter

Title Card Photo Credit: Mike Blabac https://www.blabacphoto.com

Disclaimer: https://hubermanlab.com/disclaimer