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“Fuel the Mind, Heal the Gut, Reclaim Immunity”
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Show Notes:
Most Lupus physicians, specialists, and rheumatologists are focused on ordering tests, and prescribing medication. But there are several areas which are commonly overlooked and these mistakes can cause inflammation to increase over time, without resolution

1. Ignoring Bowel Movements The inflammation in lupus starts with the gut. And this also applies to sjrogrens and mixed connective tissue disease, which are also ANA+ autoimmune conditions. Mucosa Associated Lymphatic Tissue (MALT), spleen, liver, AeroDigestive tract contains 80% of the body's immune system. American Gut Project Top Tier Research Universities are able to predict autoimmune inflammation, exacerbation, and severity, based on the type of bacteria in the stool. Gut microbiome optimization therefore is very important. Frequent regular bowel movements are desirable to prevent inflammation. Otherwise you get overgrowth of bacteria, sometimes called SIBO, or IMO if the bacterial produce methane. These bacteria cause the intestinal permeability to increase, result in leaky gut. There are tests you can do for SIBO, IMO, methane production, and Zonulin metabolites for leaky gut. C difficile colitis, also called clostridium bacteria, is another type of opportunistic infection from bacterial overgrowth. You can also get overgrowth of funguses such as Candida, which results in histamine intolerance in lupus, sjrogrens, and mixed connective tissue disease.

2. Too much sugar, processed foods. There are several concurrent biochemical pathways of inflammation in ANA+autoimmune disease that get activated. Reactive oxygen species, oxidative damage. Fatty acid synthase (FAS), hormonesensitive lipase (HSL), and peroxisome proliferatoractivated receptor gamma (PPARγ), nuclear factorkappa B (NFκB) dysregulation. If you avoid these foods, you can activate protective pathways, that are antiinflammatory in nature. These can prevent lupus, sjrogrens, and mixed connective tissue disease. These include NADPH oxidase and xanthine oxidase, superoxide dismutase (SOD), catalase, and glutathione peroxidase (GPx)

3. Deficiency in Phytonutrients Long term paleo, carnivore, Atkins, weight watchers diets can be deficient in plant base micronutrients. These micronutrients are capable of reversing inflammation seen in lupus, sjrogrens, and mixed connective tissue diesase

4. Ignoring stress and trauma most people with ANA+ autoimmune disease have significant stress in their lives

5. Poor Sleep can activate inflammatory factors which make ANA+ autoimmune diseases such as lupus, mixed connective tissue, and sjrogrens

6. Sedentary Lifestyle exercise helps reverse inflammation in lupus, sjrogrens, and mixed connective tissue disorder

00:0001:50: Introduction
01:5107:56: Bowel Movements Effect Lupus
07:5710:48: Impact of Sugars and Processed Food on Lupus
10:4913:49: Phytonutrient deficiency in Lupus
13:5016:09: How Stress and Trauma Impacts Your Lupus
16:1016:48: Sleep Habits and Lupus
16:4918:19: Exercise Importance for Lupus
18:2019:33: Outro

Note:
Although I am a licensed, and practicing surgeon, with over a decade of experience helping people overcome inflammatory diseases such as ANA+, lupus, sjrogrens, and mixed connective tissue disease the presented material is intended for educational purposes only and should not be construed as medical advice. Please use your best judgment and consult with a healthcare professional regarding your needs.

If you are looking for personalized medical support, visit MGIclinic.com to work with me.

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"As always: Be TRUE to yourself. Surround yourself with people who affirm your wellbeing. Find a doctor who will slow down to listen. Find one who carefully considers your concerns and most of allfind one who cares."

Dr. Chanu R. Dasari MD