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You Don't Have to Have Testosterone Blockers to Transition Feminine

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Spectrum: The Other Clinic

Transgender Feminizing Hormone Therapy
There are updated (more concise) videos on this topic now on the channel
Trans women and others seeking some type of feminizing HRT are often placed on Testosterone blockers in order to drop their Testosterone levels. And they are often advised that they HAVE to have this. However, that is simply untrue. Most people can easily use a regimen of only Estrogen to suppress their body's production of Testosterone naturally.

**For those wondering about clot risk. There have been, surprisingly, a decent amount of studies done on this, though many are just method versus method (ex: oral vs transdermal) to see which had more risk but doesn't mention overall risk. Here is one cited from around 2016 on clot risk for trans women specifically, with link below it: Arnold JD, Sarkodie EP, Coleman ME, Goldstein DA. Incidence of Venous Thromboembolism in Transgender Women Receiving Oral Estradiol. J Sex Med. 2016 Nov;13(11):17731777. doi: 10.1016/j.jsxm.2016.09.001. Epub 2016 Sep 23. PMID: 27671969.
https://pubmed.ncbi.nlm.nih.gov/27671...

Oversimplification of the study above: 676 trans women in the study and 0.15% had a clot event. Was the study perfect? Not many are, and that's why you have to look at a lot of them and draw conclusions after. However, the point is made here. Threat of clots is not the nightmare that providers oftentimes use in order to gatekeep hormone therapy. Certainly one’s overall health, goals, and age have to be considered when choosing a regimen. And some may have to opt for low dose Estrogen with a Testosterone blocker due to individual risk factors at play (cancer, blood disorders, previous clots).

***For those who asked for evidence of T suppression with elevated Estradiol levels...
This is basic endocrinology science and can be found in any endocrine textbook if you look up how the hypothalamicpituitarygonadal axis works. These videos are done to bring awareness to trans medical issues and be food for thought. Conversation starters. They involve knowledge sharing from our healthcare providers from their years of practice experience. Again, keep in mind we do these videos on our own free time to help spread awareness, not as a scholarly endeavor. And not as medical advice.

That being said, if your healthcare provider doesn’t understand how the sex hormones of the endocrine system interact with the hypothalamus and pituitary, then they likely shouldn’t be prescribing trans HRT in the first place.

NOT INTENDED TO BE TAKEN FOR OFFICIAL MEDICAL ADVICE, IT IS INFORMATIONAL ONLY

posted by Pozellald