Mayim Bialik may have brought joy to millions on "The Big Bang Theory," but the comedy stopped when the cameras were off. From the sudden death of a costar to her ongoing mental health struggles, Bialik's offscreen life is no laughing matter.

#MayimBialik #TheBigBang #Tragedy

Car accident | 0:00
Getting a divorce | 1:00
Her father's death | 2:02
Accusations of victim blaming | 3:09
Living with OCD | 4:40
Eating disorder | 5:31
Backlash for vaccine comments | 6:24
Criticism as host of Jeopardy! | 7:40
Death of a costar | 8:42

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