#Insulin #Diabetes #InsulinFunction #InsulinTypes #InsulinMetabolism #InsulinRegulation

Insulin Function Types | Synthesis Secretion & Regulation | Diabetes

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▬▬▬▬▬▬▬▬▬▬ Contents of this video ▬▬▬▬▬▬▬▬▬▬

00:00:00 What Is Insulin?
00:00:35 Objectives
00:01:00 Synthesis Of Insulin
00:02:36 Endocrine Function Of Pancreas
00:02:52 Islets Of Langerhans
00:04:25 Different Types Of Cells
00:05:40 What Are Alpha And Beta Cells?
00:08:47 What Are Delta Cella?
00:09:38 What Are F Cells?
00:10:20 Function Of Beta Cells?
00:15:24 Function Of Alpha Cells?
00:18:04 Function Of Delta Cells?
00:20:50 Function Of F Cells
00:21:12 Blood Flow To Islets Of Langerhans And Flow Of Insulin
00:26:00 How A Beta Cell Synthesizes Insulin
00:55:18 Mechanism Of Secretion Of Insulin From Cells
00:58:00 Role Of Glucose Transporters Glut 2
01:04:50 Role Of Glucokinase
01:05:40 Mechanism Of Phosphorylation
01:10:30 Role Of Potassium Channels
01:17:45 Sensing The Change To Open Calcium Channel
01:20:52 Release Of C Peptide And Insulin
01:21:21 Fast Review
01:26:50 Mody
01:31:40 Sulphonylureas
01:33:22 Meglitinides
01:34:33 Diazoxide
01:38:22 Insulinoma
01:40:14 Regulation Of Synthesis Of Insulin
01:52:32 Role Of Incretins
02:06:09 Exenatides
02:07:44 Sitagliptin
02:09:50 Clinical Importance
02:13:44 Other Hormones That Effect Insulin Secretion
02:19:05 Role Of Ans In Release Of Insulin
02:24:53 Somatostatin
02:30:54 What Is C Peptide And Its Functions



Insulin is synthesized as preproinsulin and processed to proinsulin. Proinsulin is then converted to insulin and Cpeptide and stored in secretary granules awaiting release on demand. Insulin synthesis is regulated at both the transcriptional and translational level.

The major purpose of insulin is to regulate the body's energy supply by balancing micronutrient levels during the fed state [30]. Insulin is critical for transporting intracellular glucose to insulindependent cells/tissues, such as liver, muscle, and adipose tissue.

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