A person cannot be diagnosed with both orthostatic hypotension and POTS simultaneously, as they are mutually exclusive conditions. In orthostatic hypotension, blood pressure drops upon standing, and the heart rate does not increase enough to compensate, leading to symptoms like fainting or blacking out due to cerebral hypoperfusion. In POTS, the heart rate increases excessively upon standing to compensate for the drop in blood pressure, preventing syncope or loss of consciousness.

Let's cover a case study of a patient diagnosed with orthostatic hypotension due to small fiber neuropathy, where the blood pressure drops upon standing, and the heart rate increase is insufficient to maintain adequate cerebral perfusion, leading to syncope events. Proper diagnosis is crucial for determining the appropriate treatment approach, whether addressing the underlying neuropathy for orthostatic hypotension or managing POTS symptoms.

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