At a population level, male testosterone levels and reproductive health are plummeting at a precipitous rate. These changes cannot be accounted for solely by comorbid conditions such as metabolic syndrome.

There appears to be other influencing factors, one of which is likely the dramatic, damaging effect of endocrine disruptors. Toxins such as phthalates, BPA, atrazine, phytoestrogens, and birth control have polluted our food, water supply, personal care products and everyday household products. Literature has demonstrated a clear association between exposure to endocrine disruptors and hypogonadism and infertility. Extensive published studies have also shown the direct epigenetic effects of exposure, confirming a likely causative effect.

The keys to mitigating the harmful effects of endocrine disruptors include limiting exposure and upregulating detox pathways through personalized epigenetic lifestyle intervention.