Pistache is an 18yearold female spayed domestic shorthair cat belonging to Sylvie Bermingham. Pistache was diagnosed with an inoperable oral squamous cell carcinoma (aggressive oral cancer) in late May of 2008. She had a large tumor between her mandibles (lower jaw) and also had metastatic disease in the draining lymph nodes (somewhat unusual for oral squamous cell carcinoma). Pistache's tumor responded wonderfully to an alternating protocol combining mitoxantrone and carboplatin, two chemotherapy agents that are frequently used in cats. She ate better, gained weight, and is still doing well a year after diagnosis. This condition normally has a 1 to 3 month prognosis for survival when inoperable. For more information, please visit www.ACVIM.org or email [email protected].