Neuroleptic Malignant Syndrome | Causes, Pathophysiology, Symptoms, Diagnosis, Treatment

Neuroleptic Malignant Syndrome (NMS) is a very rare but potentially lifethreatening condition that is caused by excessive dopamine (D2 receptor) blockade. Neuroleptic Malignant Syndrome can be caused by the rapid increase in dose of a dopamine D2 antagonist or the abrupt withdrawal of a dopamine agonist medication. In this lesson, we discuss the signs and symptoms of NMS, including how it’s diagnosed and how it’s treated.

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JJ

REFERENCES:
Neuroleptic Malignant Syndrome (StatPearls)
https://www.ncbi.nlm.nih.gov/books/NB...

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