A drug based on a compound in hallucinogenic mushrooms can improve the symptoms of severe depression for up to 12 weeks, a trial has shown.

A 25mg tablet of psilocybin puts patients in a dreamlike state and makes psychological therapy more likely to succeed.

But the shortterm sideeffects could be frightening and support must always be on hand, the researchers said.

Experts added larger studies with a much longer followup are still needed.

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