Ofatumumab is a bcell depleting agent which had two successful clinical trials for multiple sclerosis (ASCLEPIOS I and ASCLEPIOS II) where it was compared against the pill Aubagio (teriflunomide). In this video, I review the clinical trial results looking at relapses, MRI lesions, serum neurofilament, and brain atrophy. We also look at side effects of the drug in the trial.

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Dr. Brandon Beaber is a boardcertified neurologist with subspecialty training in multiple sclerosis and other immunological diseases of the nervous system. He is a partner in the Southern California Permanente Medical Group and practices in Downey, California (South Los Angeles). He has several publications on MS epidemiology and has participated in clinical trials for MS therapeutics. You can follow him on twitter @Brandon_Beaber where he regularly posts about MS news and research.

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The video material by Dr. Brandon Beaber is general educational material on health conditions and is not intended to be used by viewers to diagnose or treat any individual's medical condition. Specifically, this material is not a substitute for individualized diagnostic and treatment advice by a qualified medical/health practitioner, licensed in your jurisdiction, who has access to the relevant information available from diagnostic testing, medical interviews, and a physical examination. To the extent that Dr. Beaber endorses any lifestyle change, behavioral intervention, or supplements, the viewer should consult with a qualified healthcare professional to determine the safety and efficacy of the intervention in light of their individualized information.