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Asymmetric Organocatalysis: The 2021 Nobel Prize

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Chemiolis

Correction for 9:15 I meant to say nonpolar.

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In this video I am following a method which uses asymmetric organocatalysis with the catalyst LProline. This method (from 2022) is a prime example of how the discovery of organocatalysis in 2000 is still used today and how the 2021 nobel prize shined a light on it. In the procedure, a bicyclic enal is synthesized, which is a key intermediate for the synthesis of several relevant hormones in medicine.

Procedure:
http://www.orgsyn.org/demo.aspx?prep=...

posted by arofunner94