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This is different from antinuclear antibodies (ANA) which are antibodies against the nucleus.
Antineutrophilic cytoplasmic antibodies (ANCA) have several patterns; the most important two being the cytoplasmic ANCA (cANCA) and the perinuclear ANCA (pANCA).
Antineutrophilic cytoplasmic antibodies (ANCA) are associated with vasculitis, such as granulomatosis with polyangiitis (Wegener granulomatosis), microscopic polyangiitis, eosinophilic granulomatosis with polyangiitis (ChurgStrauss), rapidlyprogressive glomerulonephritis (RPGN), antiglomerular basement membrane antibodies (antGBM or Goodpasture's syndrome), as well as inflammatory bowel diseaseassociated. vasculitis.

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In brief, Antineutrophilic cytoplasmic antibodies (ANCA) are IgG autoantibodies against the cytoplasm of the neutrophils and monocytes​ and are associated with vasculitis, but they don't correlate with disease activity or symptoms. If you like my videos, please consider leaving a tip at https://www.paypal.me/perfectionalis/
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